Restriction digests of the clone give the following sizes (kb): EcoRI--7.1; HindIII--7.1; BamHI--4.4, 1.0, 0.53, 0.49, 0.47; PstI--3.8, 2.0, 1.1; XbaI--6.0, 0.72; EcoRI/HindIII--4.1, 2.65, consistent with deposited DNA. Codominant segregation was observed in 47 three-generation families. The TaqI polymorphism has not yet been examined by three-generation family studies. Isolated from cosmid EFZ38. Enzyme(s) not detecting polymorphism: MspI. |